PRLD

Prelude Therapeutics Incorporated Common Stock (PRLD)

Stock · NASDAQ · Health Care

$3.26as of 10/16/2026

AI Market Commentary

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Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.

October 13, 2026

PRLD announces collaboration and supply deal with Eli Lilly. Prelude Therapeutics disclosed a collaboration and supply agreement with Eli Lilly. The arrangement will have Prelude provide its CDK4/6 inhibitor abemaciclib and oral estrogen receptor antagonist imlunestrant for Lilly‑led clinical trials. Partnering with a large pharmaceutical company may expand Prelude's development pipeline and potential revenue sources. The stock is currently near its long‑term support level.

Active signals

Resistance level
$4.27
Industry
Biotechnology: Pharmaceutical Preparations

What PRLD's price did in the 20 trading sessions after each past signal, compared with any 20-session window over the same period.

SignalTimesMedian 20-session returnHigher after 20 sessions
Volume Spike43-0.3%49%
Bollinger Band Breakout30+5.4%67%
Bollinger Band Breakdown20+9.3%55%
200-Day Moving Average TouchActive now13-6.9%23%
Any 20-session window (baseline)-0.3%49%

Computed by MarketWall from daily closing prices since May 18, 2022. Returns are close-to-close and don't include dividends. Past results describe what happened before; they are not a forecast and not investment advice.

About PRLD

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and othe…

Sector
Health Care
Industry
Biotechnology: Pharmaceutical Preparations
Employees
79

Fundamentals

1-day range
$3.3$3.5
Market cap
$372.74M
P/E (trailing)
—
P/E (forward)
-6.11
EPS (trailing)
$-0.73
Dividend yield
—
Beta
1.18
Avg. volume
479.1K
52-week range
$1.16$6.83
Next earnings: November 11, 2026 · EPS estimate $-0.14

How Prelude Therapeutics Incorporated Common Stock Makes Money

Where the revenue actually goes — FY2025 annual results

market-wall.comTotalRevenue$12.14MR&D$94.30M (777%)SG&A$22.41M (185%)PRLD

Source: 10-K filed Mar 10, 2026 · via SEC EDGAR / Finnhub

Operating Income-$104.57M(-861%)

Forecasts

5 analyst ratings

Buy 89%
Hold 11%
Sell 0%
1-year price forecast
High
$12
+268.1%
Median
$10
+206.7%
Low
$6
+84.0%

Prelude Therapeutics Incorporated Common Stock Competitors

Chosen by industry and closest market cap.

  • PRLD
    Prelude Therapeutics Incorporated Common Stock
    $3.26
    ▼ 1.81%
    Market cap $372.74MP/E —
    $1.16$6.83
  • UPB
    Upstream Bio Inc. Common Stock
    $2.76
    ▼ 18.10%
    Market cap $373.87MP/E —
    $3.29$33.68
  • DMAC
    DiaMedica Therapeutics Inc. Common Stock
    $7.57
    ▼ 5.85%
    Market cap $364.79MP/E —
    $5.25$10.42
  • RCKT
    Rocket Pharmaceuticals Inc. Common Stock
    $2.18
    ▼ 7.63%
    Market cap $386.55MP/E —
    $2.42$5.45
  • NATR
    Nature's Sunshine Products Inc. Common Stock
    $12.64
    ▲ 0.00%
    Market cap $357.68MP/E 12.66
    $12.8$28.14
  • ENTA
    Enanta Pharmaceuticals Inc. Common Stock
    $11.1
    ▼ 3.23%
    Market cap $387.91MP/E —
    $10.2$17.15
  • ZNTL
    Zentalis Pharmaceuticals Inc. Common Stock
    $2.13
    ▼ 4.91%
    Market cap $355.93MP/E —
    $1.21$6.95

P/E shows — for peers not currently carrying a live signal of their own.

Latest news

Insider Activity

Insider Actions →
Acquired
8.56M
Disposed
1.41M
  • Victor Sandor · June 9, 2026 · Grant
    38.0K
  • Dorton Katina · June 9, 2026 · Grant
    38.0K
  • David P. Bonita · June 9, 2026 · Grant
    38.0K
  • Babler Martin · June 9, 2026 · Grant
    38.0K
  • Paul A. Friedman · June 9, 2026 · Grant
    38.0K
  • BAKER JULIAN · June 9, 2026 · Grant
    38.0K
  • Morris Charles Q · May 1, 2026 · Grant
    450.0K @ $4.7
  • RA Capital Healthcare Fund LP · April 27, 2026 · J
    1.41M
  • David P. Bonita · April 21, 2026 · Buy
    1.13M @ $4.44
  • David P. Bonita · April 21, 2026 · Buy
    1.69M @ $4.44
  • ORBIMED ADVISORS LLC · April 21, 2026 · Buy
    1.13M @ $4.44
  • ORBIMED ADVISORS LLC · April 21, 2026 · Buy
    1.69M @ $4.44
  • BAKER JULIAN · April 21, 2026 · Buy
    2.14M @ $4.44
  • BAKER JULIAN · April 21, 2026 · Buy
    114.6K @ $4.44

Institutional Ownership

March 31, 2026

Total shares held
30.63M
Total value held
$102.81M
Institutional holders
52
Top holders this quarter
  • Unknown10.91M
  • Unknown10.12M
  • Unknown1.59M
  • Unknown1.23M
  • Unknown947.0K
  • Unknown923.6K
  • Unknown558.3K
  • Unknown511.5K
  • Unknown382.7K
  • Unknown358.9K

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