OBIO

Orchestra BioMed Holdings Inc. Ordinary Shares (OBIO)

Stock · NASDAQ · Health Care

$5.44as of 10/16/2026

AI Market Commentary

AI-generatedAll commentary →

Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.

September 27, 2026

OBIO Shares Rise 5.2% Amid Positive Momentum. Orchestra BioMed Holdings (OBIO) shares recently increased by 5.2%, a move that some observers see as a sign of strengthening momentum. The stock currently trades within its 52-week range of $2.20 to $6.48. Analysts maintain an average price target of $12.14, suggesting a significant gap between the current market price and professional estimates.

Active signals

Support level
$3.92
Industry
Medicinal Chemicals and Botanical Products

What OBIO's price did in the 20 trading sessions after each past signal, compared with any 20-session window over the same period.

SignalTimesMedian 20-session returnHigher after 20 sessions
Volume Spike40-0.9%45%
Bollinger Band Breakout26-1.0%46%
Bollinger Band BreakdownActive now19+2.8%68%
200-Day Moving Average TouchActive now17-7.4%41%
Any 20-session window (baseline)-0.3%49%

Computed by MarketWall from daily closing prices since May 18, 2022. Returns are close-to-close and don't include dividends. Past results describe what happened before; they are not a forecast and not investment advice.

About OBIO

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodula…

Sector
Health Care
Industry
Medicinal Chemicals and Botanical Products
Employees
86

Fundamentals

1-day range
$5.42$5.87
Market cap
$248.50M
P/E (trailing)
—
P/E (forward)
-3.65
EPS (trailing)
$-1.00
Dividend yield
—
Beta
0.55
Avg. volume
300.3K
52-week range
$3.1$6.5
Next earnings: November 5, 2026 · EPS estimate $-0.40confirmed

How Orchestra BioMed Holdings Inc. Ordinary Shares Makes Money

Where the revenue actually goes — FY2025 annual results

market-wall.comTotalRevenue$33.48MR&D$58.19M (174%)SG&A$26.91M (80%)Cost of Revenue$190.0K (1%)OBIO

Source: 10-K filed Mar 12, 2026 · via SEC EDGAR / Finnhub

Gross Profit$33.29M(99%)
Operating Income-$51.81M(-155%)

Forecasts

7 analyst ratings

Buy 85%
Hold 15%
Sell 0%
1-year price forecast
High
$20
+268.0%
Median
$11
+102.4%
Low
$9
+65.6%

Orchestra BioMed Holdings Inc. Ordinary Shares Competitors

Chosen by industry and closest market cap.

  • OBIO
    Orchestra BioMed Holdings Inc. Ordinary Shares
    $5.45
    ▼ 5.05%
    Market cap $248.50MP/E —
    $3.1$6.5
  • NAGE
    Niagen Bioscience Inc. Common Stock
    $2.49
    ▼ 3.49%
    Market cap $240.54MP/E 12.74
    $2.51$7.95
  • USNA
    USANA Health Sciences Inc. Common Stock
    $15.54
    ▲ 1.04%
    Market cap $274.91MP/E 32.28
    $12.57$23.59
  • SNDL
    SNDL Inc. Common Shares
    $1.25
    ▲ 3.31%
    Market cap $312.36MP/E —
    $1.13$2.57
  • ACB
    Aurora Cannabis Inc. Common Shares
    $3.99
    ▼ 2.68%
    Market cap $184.63MP/E —
    $3.59$8.75
  • MDWD
    MediWound Ltd. Ordinary Shares
    $11.85
    ▼ 2.95%
    Market cap $183.44MP/E —
    $11.9$20.03
  • CGC
    Canopy Growth Corporation Common Shares
    $0.713
    ▼ 3.13%
    Market cap $400.49MP/E —
    $0.995$3.28

P/E shows — for peers not currently carrying a live signal of their own.

Latest news

Insider Activity

Insider Actions →
Acquired
12.0K
Disposed
93.0K

Institutional Ownership

March 31, 2026

Total shares held
22.86M
Total value held
$96.97M
Institutional holders
62
Top holders this quarter
  • Unknown8.31M
  • Unknown5.04M
  • Unknown2.20M
  • Unknown1.00M
  • Unknown896.7K
  • Unknown702.5K
  • Unknown635.7K
  • Unknown485.5K
  • Unknown402.6K
  • Unknown265.5K

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