OBIO · Orchestra BioMed Holdings Inc. Ordinary Shares
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| RTW INVESTMENTS, LP 10% Owner | ▼ Sell | Open Market | 9,556,063 Shares held | 4/27/2026 | View profile |
| PERCEPTIVE ADVISORS LLC Director | ▲ Buy | Open Market | 5,292,556 Shares held | 8/1/2025 | View profile |
| Roderick Wong Chief Executive Officer | ▲ Buy | Open Market | 2,808,512 Shares held | 1/24/2023 | View profile |
| HSAC 2 Holdings, LLC 10% Owner | ▼ Sell | Other | 1,705,705 Shares held | 8/5/2024 | View profile |
| Sherman Darren See Remarks | ▼ Sell | Open Market | 1,119,402 Shares held | 10/1/2026 | View profile |
| Taylor Andrew Lawrence Chief Financial Officer | ▼ Sell | Tax Withholding | 589,989 Shares held | 8/26/2026 | View profile |
| Hochman David P See Remarks | ▼ Sell | Tax Withholding | 432,916 Shares held | 9/10/2026 | View profile |
| Little William Reed See Remarks | ▲ Buy | Open Market | 307,859 Shares held | 5/30/2024 | View profile |
| Kaswan Michael Chief Financial Officer | ▲ Buy | Option Exercise | 162,574 Shares held | 4/12/2023 | View profile |
| Mika Yuval See Remarks | ▲ Buy | Grant | 158,905 Shares held | 5/8/2024 | View profile |
| Jason Aryeh Director | ▲ Buy | Open Market | 118,118 Shares held | 5/18/2026 | View profile |
| Fain Eric S Director | ▼ Sell | Tax Withholding | 99,630 Shares held | 8/12/2026 | View profile |
| Mack John Prosper Director | ▼ Sell | Tax Withholding | 66,544 Shares held | 8/12/2026 | View profile |
| Yanchik Connealy Pamela Chief Financial Officer | ▲ Buy | Grant | 66,038 Shares held | 6/23/2026 | View profile |
| Pacitti David Director | ▼ Sell | Tax Withholding | 54,750 Shares held | 8/12/2026 | View profile |
| Papandreou George See Remarks | ▲ Buy | Grant | 42,000 Shares held | 5/8/2024 | View profile |
| Cleary Chris Director | ▼ Sell | Tax Withholding | 29,153 Shares held | 8/12/2026 | View profile |
| Smith Geoffrey Wade Director | ▲ Buy | Grant | 20,913 Shares held | 7/20/2023 | View profile |
| Aiello Joshua Principal Accounting Officer | ▼ Sell | Tax Withholding | 18,441 Shares held | 8/26/2026 | View profile |
| ROSE ERIC A MD Director | ▲ Buy | Grant | 7,544 Shares held | 6/20/2024 | View profile |
Transaction History
| Sherman Darren | ▼ Sell | Open Market | 15,000 | $95K | 10/1/2026 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $19K | 9/10/2026 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $19K | 9/10/2026 |
| Hochman David P | ▲ Buy | Open Market | 10,000 | $48K | 9/3/2026 |
| Sherman Darren | ▼ Sell | Open Market | 15,000 | $74K | 9/1/2026 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 3,076 | $16K | 8/26/2026 |
| Aiello Joshua | ▼ Sell | Tax Withholding | 203 | $1K | 8/26/2026 |
| Sherman Darren | ▲ Buy | Open Market | 2,000 | $11K | 8/26/2026 |
| Sherman Darren | ▼ Sell | Tax Withholding | 4,925 | $26K | 8/26/2026 |
| Pacitti David | ▼ Sell | Tax Withholding | 3,761 | $17K | 8/12/2026 |
| Fain Eric S | ▼ Sell | Tax Withholding | 5,145 | $23K | 8/12/2026 |
| Mack John Prosper | ▼ Sell | Tax Withholding | 4,885 | $22K | 8/12/2026 |
| Cleary Chris | ▼ Sell | Tax Withholding | 4,238 | $19K | 8/12/2026 |
| Sherman Darren | ▼ Sell | Open Market | 15,000 | $61K | 8/3/2026 |
| Sherman Darren | ▼ Sell | Open Market | 15,000 | $64K | 7/1/2026 |
| Mack John Prosper | ▼ Sell | Tax Withholding | 3,510 | $0 | 6/24/2026 |
| Fain Eric S | ▼ Sell | Tax Withholding | 4,261 | $0 | 6/24/2026 |
| Pacitti David | ▼ Sell | Tax Withholding | 3,784 | $0 | 6/24/2026 |
| Cleary Chris | ▼ Sell | Tax Withholding | 3,510 | $0 | 6/24/2026 |
| Fain Eric S | ▲ Buy | Grant | 17,327 | $0 | 6/23/2026 |
| Pacitti David | ▲ Buy | Grant | 17,327 | $0 | 6/23/2026 |
| Yanchik Connealy Pamela | ▲ Buy | Grant | 17,327 | $0 | 6/23/2026 |
| Mack John Prosper | ▲ Buy | Grant | 34,653 | $0 | 6/23/2026 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 36,352 | $146K | 6/10/2026 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $13K | 6/10/2026 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $13K | 6/10/2026 |
| Hochman David P | ▲ Buy | Open Market | 5,000 | $19K | 6/1/2026 |
| Sherman Darren | ▼ Sell | Open Market | 15,000 | $58K | 6/1/2026 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 3,076 | $12K | 5/28/2026 |
| Sherman Darren | ▼ Sell | Tax Withholding | 4,925 | $20K | 5/28/2026 |
| Jason Aryeh | ▲ Buy | Open Market | 665 | $2K | 5/18/2026 |
| Jason Aryeh | ▲ Buy | Open Market | 8,971 | $35K | 5/15/2026 |
| Hochman David P | ▲ Buy | Open Market | 5,000 | $19K | 5/15/2026 |
| Fain Eric S | ▲ Buy | Open Market | 20,000 | $83K | 5/14/2026 |
| RTW INVESTMENTS, LP | ▼ Sell | Other | 1,250,032 | $125 | 4/27/2026 |
| RTW INVESTMENTS, LP | ▼ Sell | Open Market | 32 | $132 | 4/27/2026 |
| Sherman Darren | ▼ Sell | Tax Withholding | 33,317 | $152K | 3/25/2026 |
| Aiello Joshua | ▼ Sell | Tax Withholding | 241 | $1K | 3/25/2026 |
| Hochman David P | ▼ Sell | Tax Withholding | 32,438 | $148K | 3/25/2026 |
| Hochman David P | ▲ Buy | Open Market | 10,000 | $43K | 3/13/2026 |
| Taylor Andrew Lawrence | ▲ Buy | Grant | 181,000 | $0 | 2/12/2026 |
| Hochman David P | ▲ Buy | Grant | 504,000 | $0 | 2/12/2026 |
| Sherman Darren | ▲ Buy | Grant | 397,000 | $0 | 2/12/2026 |
| Cleary Chris | ▼ Sell | Tax Withholding | 676 | $3K | 2/5/2026 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 3,452 | $15K | 1/2/2026 |
| Aiello Joshua | ▼ Sell | Tax Withholding | 241 | $1K | 1/2/2026 |
| Sherman Darren | ▼ Sell | Tax Withholding | 5,588 | $24K | 1/2/2026 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 8,670 | $40K | 12/10/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 40,355 | $188K | 12/10/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $15K | 12/10/2025 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 3,071 | $16K | 11/25/2025 |
| Sherman Darren | ▼ Sell | Tax Withholding | 40,340 | $216K | 11/25/2025 |
| Hochman David P | ▲ Buy | Open Market | 5,000 | $20K | 11/14/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $14K | 11/13/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $14K | 11/13/2025 |
| Jason Aryeh | ▲ Buy | Open Market | 1,000 | $2K | 9/19/2025 |
| Aiello Joshua | ▼ Sell | Tax Withholding | 203 | $499 | 9/17/2025 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 16,102 | $40K | 9/17/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 40,355 | $99K | 9/17/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 3,283 | $8K | 9/17/2025 |
| Sherman Darren | ▼ Sell | Tax Withholding | 40,340 | $110K | 9/3/2025 |
| Taylor Andrew Lawrence | ▲ Buy | Open Market | 2,000 | $5K | 8/25/2025 |
| Fain Eric S | ▲ Buy | Open Market | 5,760 | $15K | 8/25/2025 |
| Sherman Darren | ▲ Buy | Open Market | 3,000 | $8K | 8/25/2025 |
| Hochman David P | ▲ Buy | Open Market | 6,000 | $15K | 8/21/2025 |
| Jason Aryeh | ▲ Buy | Grant | 15,000 | $0 | 8/7/2025 |
| Sherman Darren | ▲ Buy | Grant | 120,000 | $0 | 8/7/2025 |
| Yanchik Connealy Pamela | ▲ Buy | Grant | 15,000 | $0 | 8/7/2025 |
| Mack John Prosper | ▲ Buy | Grant | 15,000 | $0 | 8/7/2025 |
| Fain Eric S | ▲ Buy | Grant | 7,500 | $0 | 8/7/2025 |
| Fain Eric S | ▲ Buy | Grant | 7,500 | $0 | 8/7/2025 |
| Cleary Chris | ▲ Buy | Grant | 15,000 | $0 | 8/7/2025 |
| Hochman David P | ▲ Buy | Grant | 100,000 | $0 | 8/7/2025 |
| Pacitti David | ▲ Buy | Grant | 15,000 | $0 | 8/7/2025 |
| Aiello Joshua | ▲ Buy | Grant | 15,000 | $0 | 8/7/2025 |
| Hochman David P | ▲ Buy | Grant | 100,000 | $0 | 8/7/2025 |
| Taylor Andrew Lawrence | ▲ Buy | Grant | 80,000 | $0 | 8/7/2025 |
| Hochman David P | ▲ Buy | Open Market | 20,000 | $55K | 8/4/2025 |
| PERCEPTIVE ADVISORS LLC | ▲ Buy | Open Market | 700,000 | $1.9M | 8/1/2025 |
| Fain Eric S | ▼ Sell | Open Market | 2,683 | $8K | 6/26/2025 |
| Jason Aryeh | ▲ Buy | Grant | 12,422 | $0 | 6/24/2025 |
| Mack John Prosper | ▲ Buy | Grant | 12,422 | $0 | 6/24/2025 |
| Yanchik Connealy Pamela | ▲ Buy | Grant | 12,422 | $0 | 6/24/2025 |
| Fain Eric S | ▲ Buy | Grant | 12,422 | $0 | 6/24/2025 |
| Pacitti David | ▲ Buy | Grant | 12,422 | $0 | 6/24/2025 |
| Cleary Chris | ▲ Buy | Grant | 12,422 | $0 | 6/24/2025 |
| Aiello Joshua | ▼ Sell | Tax Withholding | 393 | $1K | 6/18/2025 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 28,172 | $88K | 6/11/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 34,038 | $107K | 6/11/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 5,671 | $18K | 6/11/2025 |
| Sherman Darren | ▼ Sell | Tax Withholding | 45,843 | $135K | 5/28/2025 |
| RTW INVESTMENTS, LP | ▲ Buy | Open Market | 49,900 | $149K | 4/30/2025 |
| RTW INVESTMENTS, LP | ▲ Buy | Open Market | 50,000 | $126K | 4/29/2025 |
| Hochman David P | ▲ Buy | Grant | 98,333 | $0 | 4/4/2025 |
| Sherman Darren | ▲ Buy | Grant | 115,708 | $0 | 4/4/2025 |
| Taylor Andrew Lawrence | ▲ Buy | Grant | 84,000 | $0 | 4/4/2025 |
| Aiello Joshua | ▼ Sell | Tax Withholding | 278 | $1K | 3/26/2025 |
| Hochman David P | ▼ Sell | Tax Withholding | 80,080 | $339K | 3/7/2025 |
| Cleary Chris | ▲ Buy | Grant | 10,155 | $0 | 2/3/2025 |
| Jason Aryeh | ▲ Buy | Option Exercise | 11,700 | $50K | 12/27/2024 |
| Hochman David P | ▲ Buy | Open Market | 4,000 | $19K | 12/23/2024 |
| Taylor Andrew Lawrence | ▲ Buy | Open Market | 1,000 | $5K | 12/19/2024 |
| Hochman David P | ▲ Buy | Open Market | 5,000 | $25K | 12/18/2024 |
| Taylor Andrew Lawrence | ▼ Sell | Tax Withholding | 34,403 | $173K | 12/12/2024 |
| Sherman Darren | ▼ Sell | Tax Withholding | 31,815 | $177K | 12/5/2024 |
| Hochman David P | ▲ Buy | Open Market | 1,500 | $7K | 9/25/2024 |
| Hochman David P | ▲ Buy | Open Market | 2,000 | $9K | 9/25/2024 |
| Hochman David P | ▲ Buy | Open Market | 2,000 | $9K | 9/25/2024 |
| Hochman David P | ▲ Buy | Open Market | 2,000 | $9K | 9/25/2024 |
| Hochman David P | ▲ Buy | Open Market | 2,500 | $12K | 9/24/2024 |
| Sherman Darren | ▼ Sell | Open Market | 6,904 | $37K | 9/10/2024 |
| Fain Eric S | ▼ Sell | Open Market | 1,800 | $10K | 9/10/2024 |
| Sherman Darren | ▼ Sell | Open Market | 6,804 | $37K | 9/9/2024 |
| Fain Eric S | ▼ Sell | Open Market | 1,800 | $10K | 9/9/2024 |
| Fain Eric S | ▼ Sell | Open Market | 2,000 | $11K | 9/6/2024 |
| Sherman Darren | ▼ Sell | Open Market | 6,819 | $39K | 9/6/2024 |
| Sherman Darren | ▼ Sell | Open Market | 6,961 | $41K | 9/5/2024 |
| Sherman Darren | ▼ Sell | Open Market | 6,837 | $42K | 9/4/2024 |
| Hochman David P | ▲ Buy | Open Market | 2,500 | $15K | 8/14/2024 |
| Mack John Prosper | ▲ Buy | Grant | 12,864 | $0 | 8/7/2024 |
| HSAC 2 Holdings, LLC | ▼ Sell | Other | 3,405,251 | $0 | 8/5/2024 |
| Hochman David P | ▲ Buy | Open Market | 1,000 | $7K | 6/25/2024 |
| Yanchik Connealy Pamela | ▲ Buy | Grant | 5,376 | $0 | 6/20/2024 |
| Jason Aryeh | ▲ Buy | Grant | 5,376 | $0 | 6/20/2024 |
| ROSE ERIC A MD | ▲ Buy | Grant | 5,376 | $0 | 6/20/2024 |
| Fain Eric S | ▲ Buy | Grant | 5,376 | $0 | 6/20/2024 |
| Pacitti David | ▲ Buy | Grant | 5,376 | $0 | 6/20/2024 |
| Little William Reed | ▲ Buy | Open Market | 4,000 | $28K | 5/30/2024 |
| Hochman David P | ▲ Buy | Grant | 3,000 | $15K | 5/17/2024 |
| Hochman David P | ▲ Buy | Grant | 2,000 | $10K | 5/16/2024 |
| Mika Yuval | ▲ Buy | Grant | 69,333 | $0 | 5/8/2024 |
| Papandreou George | ▲ Buy | Grant | 22,000 | $0 | 5/8/2024 |
| Hochman David P | ▲ Buy | Grant | 100,000 | $0 | 5/8/2024 |
| Hochman David P | ▲ Buy | Grant | 100,000 | $0 | 5/8/2024 |
| Sherman Darren | ▲ Buy | Grant | 176,667 | $0 | 5/8/2024 |
| Little William Reed | ▲ Buy | Grant | 53,333 | $0 | 5/8/2024 |
| Taylor Andrew Lawrence | ▲ Buy | Grant | 100,000 | $0 | 5/8/2024 |
| Pacitti David | ▲ Buy | Grant | 10,000 | $0 | 3/26/2024 |
| Smith Geoffrey Wade | ▲ Buy | Grant | 16,667 | $0 | 7/20/2023 |
| Hochman David P | ▲ Buy | Grant | 300,000 | $0 | 7/20/2023 |
| Hochman David P | ▲ Buy | Grant | 165,000 | $0 | 7/20/2023 |
| Sherman Darren | ▲ Buy | Grant | 539,667 | $0 | 7/20/2023 |
| Taylor Andrew Lawrence | ▲ Buy | Grant | 278,363 | $0 | 7/20/2023 |
| Fain Eric S | ▲ Buy | Grant | 11,667 | $0 | 7/20/2023 |
| Little William Reed | ▲ Buy | Grant | 250,526 | $0 | 7/20/2023 |
| Yanchik Connealy Pamela | ▲ Buy | Grant | 11,667 | $0 | 7/20/2023 |
| Mika Yuval | ▲ Buy | Grant | 40,000 | $0 | 7/20/2023 |
| Aiello Joshua | ▲ Buy | Grant | 5,000 | $0 | 7/20/2023 |
| ROSE ERIC A MD | ▲ Buy | Option Exercise | 2,325 | $3K | 5/17/2023 |
| ROSE ERIC A MD | ▼ Sell | Tax Withholding | 157 | $3K | 5/17/2023 |
| Fain Eric S | ▲ Buy | Option Exercise | 2,906 | $3K | 5/10/2023 |
| RTW INVESTMENTS, LP | ▼ Sell | Other | 502,133 | — | 4/13/2023 |
| Smith Geoffrey Wade | ▲ Buy | Option Exercise | 758 | — | 4/12/2023 |
| Smith Geoffrey Wade | ▲ Buy | Option Exercise | 43,761 | — | 4/12/2023 |
| Mika Yuval | ▲ Buy | Option Exercise | 8,852 | — | 4/12/2023 |
| Yanchik Connealy Pamela | ▲ Buy | Option Exercise | 758 | — | 4/12/2023 |
| Kaswan Michael | ▲ Buy | Option Exercise | 29,029 | — | 4/12/2023 |
| Jason Aryeh | ▲ Buy | Option Exercise | 11,246 | — | 4/12/2023 |
| Fain Eric S | ▲ Buy | Option Exercise | 4,796 | — | 4/12/2023 |
| Hochman David P | ▲ Buy | Option Exercise | 29,551 | — | 4/12/2023 |
| Smith Geoffrey Wade | ▲ Buy | Option Exercise | 228,073 | — | 4/12/2023 |
| Smith Geoffrey Wade | ▲ Buy | Option Exercise | 55,783 | — | 4/12/2023 |
| Hochman David P | ▲ Buy | Option Exercise | 11,160 | — | 4/12/2023 |
| Hochman David P | ▲ Buy | Option Exercise | 683 | — | 4/12/2023 |
| Sherman Darren | ▲ Buy | Option Exercise | 14,959 | — | 4/12/2023 |
| Sherman Darren | ▲ Buy | Grant | 68,189 | — | 1/26/2023 |
| RTW INVESTMENTS, LP | ▲ Buy | Grant | 2,310,000 | — | 1/26/2023 |
| Smith Geoffrey Wade | ▲ Buy | Grant | 3,488 | — | 1/26/2023 |
| Smith Geoffrey Wade | ▲ Buy | Grant | 201,319 | — | 1/26/2023 |
| Smith Geoffrey Wade | ▲ Buy | Grant | 1,049,224 | — | 1/26/2023 |
| Smith Geoffrey Wade | ▲ Buy | Grant | 256,623 | — | 1/26/2023 |
| Hochman David P | ▲ Buy | Grant | 3,140 | — | 1/26/2023 |
| Hochman David P | ▲ Buy | Grant | 51,342 | — | 1/26/2023 |
| Hochman David P | ▲ Buy | Grant | 135,947 | — | 1/26/2023 |
| Mika Yuval | ▲ Buy | Grant | 40,720 | — | 1/26/2023 |
| Kaswan Michael | ▲ Buy | Grant | 133,545 | — | 1/26/2023 |
| Yanchik Connealy Pamela | ▲ Buy | Grant | 3,488 | — | 1/26/2023 |
| Jason Aryeh | ▲ Buy | Grant | 51,738 | — | 1/26/2023 |
| Fain Eric S | ▲ Buy | Grant | 22,065 | — | 1/26/2023 |
| Roderick Wong | ▲ Buy | Open Market | 1,808,512 | $18.1M | 1/24/2023 |
| Roderick Wong | ▲ Buy | Open Market | 1,000,000 | $10.0M | 7/22/2022 |
AI Market Commentary
AI-generatedAll commentary →Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.
September 27, 2026
OBIO Shares Rise 5.2% Amid Positive Momentum
Orchestra BioMed Holdings (OBIO) shares recently increased by 5.2%, a move that some observers see as a sign of strengthening momentum. The stock currently trades within its 52-week range of $2.20 to $6.48. Analysts maintain an average price target of $12.14, suggesting a significant gap between the current market price and professional estimates.
OBIO Shares Rise 5.2% Amid Positive Momentum. Orchestra BioMed Holdings (OBIO) shares recently increased by 5.2%, a move that some observers see as a sign of strengthening momentum. The stock currently trades within its 52-week range of $2.20 to $6.48. Analysts maintain an average price target of $12.14, suggesting a significant gap between the current market price and professional estimates.