PTGX

Protagonist Therapeutics Inc. Common Stock (PTGX)

Stock · NASDAQ · Health Care

$128.94as of 10/16/2026

AI Market Commentary

AI-generatedAll commentary →

Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.

October 5, 2026

PTGX featured in recent SeekingAlpha and Benzinga articles. A SeekingAlpha column noted Johnson & Johnson’s strong catalysts while keeping a hold stance, a view that may influence sentiment toward biotech peers such as Protagonist Therapeutics. Separately, Benzinga published a piece examining how a $100 investment in PTGX ten years ago would have grown, highlighting the stock’s historical performance. These mentions reflect ongoing analyst and investor interest in the company.

Active signals

Support level
$98.36
Industry
Biotechnology: Pharmaceutical Preparations

What PTGX's price did in the 20 trading sessions after each past signal, compared with any 20-session window over the same period.

SignalTimesMedian 20-session returnHigher after 20 sessions
Volume Spike32-0.5%47%
Bollinger Band Breakout30+1.1%60%
Bollinger Band BreakdownActive now13+4.4%77%
200-Day Moving Average TouchActive now8+11.0%75%
Any 20-session window (baseline)+5.3%64%

Computed by MarketWall from daily closing prices since May 18, 2022. Returns are close-to-close and don't include dividends. Past results describe what happened before; they are not a forecast and not investment advice.

About PTGX

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development f…

Sector
Health Care
Industry
Biotechnology: Pharmaceutical Preparations
Employees
141

Fundamentals

1-day range
$130.61$136.56
Market cap
$9.40B
P/E (trailing)
107.21
P/E (forward)
-860.82
EPS (trailing)
$1.04
Dividend yield
—
Beta
1.19
Avg. volume
630.5K
52-week range
$73.08$160.81
Next earnings: November 5, 2026 · EPS estimate $2.53After Closeconfirmed

How Protagonist Therapeutics Inc. Common Stock Makes Money

Where the revenue actually goes — FY2018 annual results

market-wall.comTotalRevenue$30.93MR&D$59.50M (192%)SG&A$13.70M (44%)Tax$799.0K (3%)PTGX

Source: 10-K filed Mar 12, 2019 · via SEC EDGAR / Finnhub

Operating Income-$42.27M(-137%)

Forecasts

14 analyst ratings

Buy 95%
Hold 5%
Sell 0%
1-year price forecast
High
$225
+74.5%
Median
$176.5
+36.9%
Low
$149
+15.6%

Protagonist Therapeutics Inc. Common Stock Competitors

Chosen by industry and closest market cap.

  • PTGX
    Protagonist Therapeutics Inc. Common Stock
    $128.75
    ▼ 5.71%
    Market cap $9.40BP/E 107.21
    $73.08$160.81
  • SYRE
    Spyre Therapeutics Inc. Common Stock
    $79.9
    ▼ 0.25%
    Market cap $9.12BP/E —
    $21.01$110.18
  • IONS
    Ionis Pharmaceuticals Inc. Common Stock
    $42.94
    ▼ 2.67%
    Market cap $9.06BP/E —
    $42.08$86.74
  • RDY
    Dr. Reddy's Laboratories Ltd Common Stock
    $13.07
    ▲ 1.32%
    Market cap $10.11BP/E 31.61
    $1,101$1,415
  • CYTK
    Cytokinetics Incorporated Common Stock
    $61.95
    ▼ 3.08%
    Market cap $10.13BP/E —
    $54.3$88.31
  • PRAX
    Praxis Precision Medicines Inc. Common Stock
    $241.76
    ▼ 2.61%
    Market cap $10.32BP/E —
    $50.56$392.7
  • ALKS
    Alkermes plc Ordinary Shares
    $41.22
    ▲ 2.79%
    Market cap $8.11BP/E 99.15
    $27$55.67

P/E shows — for peers not currently carrying a live signal of their own.

Latest news

Insider Activity

Insider Actions →
Acquired
243.0K
Disposed
234.5K

Institutional Ownership

March 31, 2026

Total shares held
76.12M
Total value held
$7.77B
Institutional holders
319
Top holders this quarter
  • Unknown9.78M
  • Unknown6.35M
  • Unknown5.18M
  • Unknown5.06M
  • Unknown3.60M
  • Unknown3.48M
  • Unknown3.12M
  • Unknown2.89M
  • Unknown2.45M
  • Unknown2.16M

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