DNLI

Denali Therapeutics Inc. Common Stock (DNLI)

Stock · NASDAQ · Health Care

$17.61as of 10/16/2026

AI Market Commentary

AI-generatedAll commentary →

Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.

October 9, 2026

Denali Therapeutics Shares Test Fair Value Amid Pullback. Denali Therapeutics shares have pulled back, testing the $19.37 support level. The 14‑day RSI sits at 30, indicating a possible oversold condition, while the support_reject signal suggests the level may hold. Analysts average a target of $36.06, with a range of $27 to $42, well above the current price and the 52‑week low of $13.75. The pullback could be seen as a chance to assess fair value.

Active signals

Resistance level
$18.93
Industry
Biotechnology: Biological Products (No Diagnostic Substances)

What DNLI's price did in the 20 trading sessions after each past signal, compared with any 20-session window over the same period.

SignalTimesMedian 20-session returnHigher after 20 sessions
Volume Spike38-0.8%50%
Bollinger Band Breakout240.0%50%
Bollinger Band Breakdown18+1.6%56%
200-Day Moving Average TouchActive now17-6.4%24%
Any 20-session window (baseline)-0.6%48%

Computed by MarketWall from daily closing prices since May 18, 2022. Returns are close-to-close and don't include dividends. Past results describe what happened before; they are not a forecast and not investment advice.

About DNLI

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (S…

Sector
Health Care
Industry
Biotechnology: Biological Products (No Diagnostic Substances)
Employees
503

Fundamentals

1-day range
$18.01$18.53
Market cap
$3.92B
P/E (trailing)
—
P/E (forward)
-7.59
EPS (trailing)
$-2.84
Dividend yield
—
Beta
1.06
Avg. volume
1.55M
52-week range
$13.75$27.3
Next earnings: November 5, 2026 · EPS estimate $-0.37confirmed

How Denali Therapeutics Inc. Common Stock Makes Money

Where the revenue actually goes — FY2023 annual results

market-wall.comTotalRevenue$330.53MR&D$423.88M (128%)SG&A$103.35M (31%)Tax$30.0K (0%)DNLI

Source: 10-K filed Feb 28, 2024 · via SEC EDGAR / Finnhub

Operating Income-$196.70M(-60%)

Forecasts

16 analyst ratings

Buy 92%
Hold 8%
Sell 0%
1-year price forecast
High
$42
+138.6%
Median
$35
+98.8%
Low
$27
+53.4%

Denali Therapeutics Inc. Common Stock Competitors

Chosen by industry and closest market cap.

  • DNLI
    Denali Therapeutics Inc. Common Stock
    $17.61
    ▼ 3.98%
    Market cap $3.92BP/E —
    $13.75$27.3
  • RLAY
    Relay Therapeutics Inc. Common Stock
    $16.28
    ▼ 5.90%
    Market cap $3.78BP/E —
    $5.95$21.27
  • ADPT
    Adaptive Biotechnologies Corporation Common Stock
    $24.02
    ▼ 6.10%
    Market cap $3.77BP/E —
    $12$30.74
  • CRSP
    CRISPR Therapeutics AG Common Shares
    $49.25
    ▼ 4.41%
    Market cap $4.99BP/E —
    $44.12$75.06
  • KOD
    Kodiak Sciences Inc Common Stock
    $85.75
    ▼ 2.69%
    Market cap $2.84BP/E —
    $10.94$104
  • BEAM
    Beam Therapeutics Inc. Common Stock
    $23.47
    ▼ 5.10%
    Market cap $2.81BP/E —
    $20.23$38.26
  • TARS
    Tarsus Pharmaceuticals Inc. Common Stock
    $68.07
    ▼ 4.11%
    Market cap $2.81BP/E —
    $53.89$91.53

P/E shows — for peers not currently carrying a live signal of their own.

Latest news

Insider Activity

Insider Actions →
Acquired
108.9K
Disposed
50.9K

Institutional Ownership

March 31, 2026

Total shares held
140.66M
Total value held
$2.47B
Institutional holders
263
Top holders this quarter
  • Unknown13.03M
  • Unknown12.07M
  • Unknown8.52M
  • Unknown7.01M
  • Unknown6.27M
  • Unknown6.15M
  • Unknown4.58M
  • Unknown4.43M
  • Unknown4.41M
  • Unknown3.73M

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