SEPN

Septerna Inc. Common Stock (SEPN)

Stock · NASDAQ · Health Care

$38.91as of 8/28/2026

Active signals

No technical signal is currently active for this symbol.

Support level
$23.7
Industry
Biotechnology: Pharmaceutical Preparations

About SEPN

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric m…

Sector
Health Care
Industry
Biotechnology: Pharmaceutical Preparations
Employees
123

Fundamentals

1-day range
$43.64$46.5
Market cap
$1.58B
P/E (trailing)
P/E (forward)
-24.33
EPS (trailing)
$-0.53
Dividend yield
Beta
Avg. volume
436.5K
52-week range
$10.74$51.1
Next earnings: November 9, 2026 · EPS estimate $-0.55

How Septerna Inc. Common Stock Makes Money

Where the revenue actually goes — FY2025 annual results

market-wall.comTotalRevenue$45.95MR&D$97.58M (212%)SG&A$29.16M (63%)Tax$12.0K (0%)SEPN

Source: 10-K filed Mar 9, 2026 · via SEC EDGAR / Finnhub

Forecasts

9 analyst ratings

Buy 100%
Hold 0%
Sell 0%
1-year price forecast
High
$62
+59.3%
Median
$51
+31.1%
Low
$38
-2.3%

Septerna Inc. Common Stock Competitors

Chosen by industry and closest market cap.

  • SEPN
    Septerna Inc. Common Stock
    $38.91
    ▼ 3.85%
    Market cap $1.58BP/E
    $10.74$51.1
  • AAPG
    Ascentage Pharma Group International American Depository Shares
    $18.28
    ▼ 2.16%
    Market cap $1.57BP/E
    $30$91.5
  • TRAX
    First Tracks Biotherapeutics Inc. Ordinary Shares
    $41.77
    ▼ 6.64%
    Market cap $1.61BP/E
    $14.72$49.91
  • INVA
    Innoviva Inc. Common Stock
    $20.97
    ▲ 0.05%
    Market cap $1.53BP/E 4.21
    $16.52$25.15
  • PAHC
    Phibro Animal Health Corporation Class A Common Stock
    $37.64
    ▲ 3.55%
    Market cap $1.51BP/E 14.51
    $28.25$60.08
  • MRVI
    Maravai LifeSciences Holdings Inc. Class A Common Stock
    $7.67
    ▼ 8.42%
    Market cap $1.66BP/E
    $2.28$9.42
  • BCAX
    Bicara Therapeutics Inc. Common Stock
    $23.42
    ▼ 5.70%
    Market cap $1.69BP/E
    $10.3$30.99

P/E shows — for peers not currently carrying a live signal of their own.

Institutional Ownership

March 31, 2026

Total shares held
45.33M
Total value held
$1.09B
Institutional holders
119
Top holders this quarter
  • Unknown7.00M
  • Unknown6.22M
  • Unknown4.40M
  • Unknown4.21M
  • Unknown3.15M
  • Unknown2.91M
  • Unknown2.00M
  • Unknown1.82M
  • Unknown1.35M
  • Unknown1.34M

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