EWTX · Edgewise Therapeutics Inc. Common Stock
View on chartInsiders & Stakes
| Novo Holdings A/S 10% Owner | ▲ Buy | Open Market | 6,071,703 Shares held | 9/14/2022 | View profile |
| ORBIMED ADVISORS LLC Director | ▲ Buy | Open Market | 443,792 Shares held | 4/3/2025 | View profile |
| Peter A. Thompson Director | ▲ Buy | Open Market | 443,792 Shares held | 4/3/2025 | View profile |
| Carruthers R Michael Chief Financial Officer | ▼ Sell | Open Market | 86,162 Shares held | 8/12/2025 | View profile |
| KOCH KEVIN President and CEO | ▼ Sell | Open Market | 52,488 Shares held | 8/12/2026 | View profile |
| Derakhshan Behrad Chief Business Officer | ▼ Sell | Open Market | 31,826 Shares held | 8/12/2026 | View profile |
| Russell Alan J Chief Scientific Officer | ▼ Sell | Open Market | 31,466 Shares held | 8/12/2026 | View profile |
| Fox Jonathan C | ▲ Buy | Grant | 25,141 Shares held | 10/1/2026 | View profile |
| Edris Badreddin | ▼ Sell | Open Market | 19,820 Shares held | 1/21/2026 | View profile |
| MOORE JOHN R General Counsel | ▼ Sell | Open Market | 17,697 Shares held | 8/12/2026 | View profile |
| Donovan Joanne M. CMO | ▼ Sell | Open Market | 8,625 Shares held | 8/13/2026 | View profile |
| Semigran Marc Chief Development Officer | ▼ Sell | Open Market | 6,716 Shares held | 12/24/2024 | View profile |
| Jonathan D. Root Director | ▼ Sell | Other | 0 Shares held | 2/25/2022 | View profile |
Transaction History
| Fox Jonathan C | ▲ Buy | Grant | 308 | $0 | 10/1/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 2,919 | $127K | 8/13/2026 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2026 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 7,031 | $0 | 8/12/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 2,839 | $124K | 8/12/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 2,779 | $121K | 8/12/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 104 | $5K | 8/12/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 800 | $36K | 8/12/2026 |
| Russell Alan J | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2026 |
| Russell Alan J | ▲ Buy | Option Exercise | 7,031 | $0 | 8/12/2026 |
| Russell Alan J | ▼ Sell | Open Market | 3,238 | $141K | 8/12/2026 |
| Russell Alan J | ▼ Sell | Open Market | 2,273 | $99K | 8/12/2026 |
| Russell Alan J | ▼ Sell | Open Market | 390 | $17K | 8/12/2026 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2026 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 6,718 | $0 | 8/12/2026 |
| MOORE JOHN R | ▼ Sell | Open Market | 2,439 | $107K | 8/12/2026 |
| MOORE JOHN R | ▼ Sell | Open Market | 59 | $3K | 8/12/2026 |
| MOORE JOHN R | ▼ Sell | Open Market | 99 | $4K | 8/12/2026 |
| MOORE JOHN R | ▼ Sell | Open Market | 2,419 | $106K | 8/12/2026 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2026 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 7,500 | $0 | 8/12/2026 |
| Derakhshan Behrad | ▼ Sell | Open Market | 2,171 | $95K | 8/12/2026 |
| Derakhshan Behrad | ▼ Sell | Open Market | 304 | $14K | 8/12/2026 |
| Derakhshan Behrad | ▼ Sell | Open Market | 150 | $7K | 8/12/2026 |
| Derakhshan Behrad | ▼ Sell | Open Market | 2,475 | $108K | 8/12/2026 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 17,969 | $0 | 8/12/2026 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 21,875 | $0 | 8/12/2026 |
| KOCH KEVIN | ▼ Sell | Open Market | 8,782 | $383K | 8/12/2026 |
| KOCH KEVIN | ▼ Sell | Open Market | 8,276 | $361K | 8/12/2026 |
| KOCH KEVIN | ▼ Sell | Open Market | 913 | $40K | 8/12/2026 |
| Russell Alan J | ▲ Buy | Option Exercise | 130,352 | $59K | 7/1/2026 |
| Russell Alan J | ▲ Buy | Option Exercise | 69,648 | $13K | 7/1/2026 |
| Russell Alan J | ▼ Sell | Open Market | 130,352 | $5.1M | 7/1/2026 |
| Russell Alan J | ▼ Sell | Open Market | 69,648 | $2.7M | 7/1/2026 |
| Fox Jonathan C | ▲ Buy | Grant | 319 | $0 | 7/1/2026 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 50,000 | $354K | 5/5/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 50,000 | $1.9M | 5/5/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 5,230 | $164K | 5/4/2026 |
| Fox Jonathan C | ▲ Buy | Grant | 339 | $0 | 4/1/2026 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 28,662 | $203K | 4/1/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 28,662 | $926K | 4/1/2026 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 21,338 | $151K | 3/31/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 21,338 | $685K | 3/31/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 9,623 | $298K | 3/27/2026 |
| Donovan Joanne M. | ▼ Sell | Open Market | 6,735 | $209K | 3/27/2026 |
| Edris Badreddin | ▲ Buy | Option Exercise | 13,690 | $5K | 1/21/2026 |
| Edris Badreddin | ▲ Buy | Option Exercise | 17,236 | $11K | 1/21/2026 |
| Edris Badreddin | ▲ Buy | Option Exercise | 10,463 | $20K | 1/21/2026 |
| Edris Badreddin | ▲ Buy | Option Exercise | 66,477 | $128K | 1/21/2026 |
| Edris Badreddin | ▲ Buy | Option Exercise | 7,605 | $5K | 1/21/2026 |
| Edris Badreddin | ▼ Sell | Open Market | 13,690 | $403K | 1/21/2026 |
| Edris Badreddin | ▼ Sell | Open Market | 17,236 | $507K | 1/21/2026 |
| Edris Badreddin | ▼ Sell | Open Market | 7,605 | $224K | 1/21/2026 |
| Edris Badreddin | ▼ Sell | Open Market | 10,463 | $308K | 1/21/2026 |
| Edris Badreddin | ▼ Sell | Open Market | 66,477 | $2.0M | 1/21/2026 |
| Fox Jonathan C | ▲ Buy | Grant | 473 | $0 | 1/2/2026 |
| Russell Alan J | ▲ Buy | Option Exercise | 100,000 | $18K | 11/12/2025 |
| Russell Alan J | ▼ Sell | Open Market | 100,000 | $2.1M | 11/12/2025 |
| Fox Jonathan C | ▲ Buy | Open Market | 10,700 | $199K | 11/11/2025 |
| Fox Jonathan C | ▲ Buy | Grant | 728 | $0 | 10/1/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 100,000 | $18K | 8/26/2025 |
| Russell Alan J | ▼ Sell | Open Market | 100,000 | $1.5M | 8/26/2025 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2025 |
| MOORE JOHN R | ▼ Sell | Open Market | 2,098 | $28K | 8/12/2025 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2025 |
| Derakhshan Behrad | ▼ Sell | Open Market | 2,491 | $33K | 8/12/2025 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2025 |
| Carruthers R Michael | ▼ Sell | Open Market | 1,428 | $19K | 8/12/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2025 |
| Russell Alan J | ▼ Sell | Open Market | 1,907 | $26K | 8/12/2025 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 17,968 | $0 | 8/12/2025 |
| KOCH KEVIN | ▼ Sell | Open Market | 7,972 | $107K | 8/12/2025 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 5,781 | $0 | 8/12/2025 |
| Donovan Joanne M. | ▼ Sell | Open Market | 2,862 | $38K | 8/12/2025 |
| Fox Jonathan C | ▲ Buy | Grant | 858 | $0 | 7/1/2025 |
| Russell Alan J | ▼ Sell | Open Market | 1,551 | $26K | 5/2/2025 |
| MOORE JOHN R | ▼ Sell | Open Market | 1,930 | $32K | 5/2/2025 |
| KOCH KEVIN | ▼ Sell | Open Market | 4,276 | $70K | 5/2/2025 |
| Donovan Joanne M. | ▼ Sell | Open Market | 5,187 | $85K | 5/2/2025 |
| Derakhshan Behrad | ▼ Sell | Open Market | 1,691 | $28K | 5/2/2025 |
| Carruthers R Michael | ▼ Sell | Open Market | 1,314 | $22K | 5/2/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 5,209 | $0 | 5/1/2025 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 5,209 | $0 | 5/1/2025 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 10,417 | $0 | 5/1/2025 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 10,417 | $0 | 5/1/2025 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 5,209 | $0 | 5/1/2025 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 5,209 | $0 | 5/1/2025 |
| Peter A. Thompson | ▲ Buy | Open Market | 372,578 | $7.5M | 4/3/2025 |
| Peter A. Thompson | ▲ Buy | Open Market | 124,193 | $2.5M | 4/3/2025 |
| ORBIMED ADVISORS LLC | ▲ Buy | Open Market | 372,578 | $7.5M | 4/3/2025 |
| ORBIMED ADVISORS LLC | ▲ Buy | Open Market | 124,193 | $2.5M | 4/3/2025 |
| Fox Jonathan C | ▲ Buy | Grant | 559 | $0 | 4/1/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 200 | $36 | 3/7/2025 |
| Russell Alan J | ▼ Sell | Open Market | 200 | $6K | 3/7/2025 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 100 | $18 | 3/7/2025 |
| KOCH KEVIN | ▼ Sell | Open Market | 100 | $3K | 3/7/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 1,200 | $216 | 2/6/2025 |
| Russell Alan J | ▼ Sell | Open Market | 1,200 | $36K | 2/6/2025 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 900 | $12K | 2/6/2025 |
| KOCH KEVIN | ▼ Sell | Open Market | 900 | $28K | 2/6/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 8,015 | $1K | 2/5/2025 |
| Russell Alan J | ▼ Sell | Open Market | 8,015 | $241K | 2/5/2025 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 8,636 | $2K | 2/5/2025 |
| KOCH KEVIN | ▼ Sell | Open Market | 8,636 | $259K | 2/5/2025 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 10,000 | $19K | 2/5/2025 |
| Derakhshan Behrad | ▼ Sell | Open Market | 10,000 | $300K | 2/5/2025 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 25,000 | $177K | 1/28/2025 |
| Donovan Joanne M. | ▼ Sell | Open Market | 25,000 | $691K | 1/28/2025 |
| Russell Alan J | ▲ Buy | Option Exercise | 100,000 | $18K | 12/30/2024 |
| Russell Alan J | ▼ Sell | Open Market | 100,000 | $2.7M | 12/30/2024 |
| Semigran Marc | ▲ Buy | Option Exercise | 29,709 | $266K | 12/24/2024 |
| Semigran Marc | ▼ Sell | Open Market | 27,980 | $830K | 12/24/2024 |
| Semigran Marc | ▼ Sell | Open Market | 1,729 | $52K | 12/24/2024 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 70,000 | $50K | 10/11/2024 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 20,922 | $15K | 9/23/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 20,922 | $578K | 9/23/2024 |
| Russell Alan J | ▲ Buy | Option Exercise | 75,000 | $14K | 9/20/2024 |
| Russell Alan J | ▼ Sell | Open Market | 74,185 | $2.1M | 9/20/2024 |
| Russell Alan J | ▼ Sell | Open Market | 815 | $24K | 9/20/2024 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 50,000 | $36K | 9/20/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 50,000 | $1.4M | 9/20/2024 |
| Donovan Joanne M. | ▼ Sell | Open Market | 7,162 | $203K | 9/20/2024 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 42,068 | $81K | 9/20/2024 |
| Derakhshan Behrad | ▼ Sell | Open Market | 42,068 | $1.2M | 9/20/2024 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 46,068 | $89K | 9/20/2024 |
| Carruthers R Michael | ▼ Sell | Open Market | 46,068 | $1.3M | 9/20/2024 |
| Carruthers R Michael | ▼ Sell | Open Market | 4,064 | $116K | 9/20/2024 |
| Carruthers R Michael | ▼ Sell | Open Market | 24,960 | $714K | 9/20/2024 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 50,000 | $97K | 9/20/2024 |
| Carruthers R Michael | ▼ Sell | Open Market | 50,000 | $1.4M | 9/20/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 1,956 | $37K | 5/2/2024 |
| Carruthers R Michael | ▼ Sell | Open Market | 2,157 | $41K | 5/2/2024 |
| Derakhshan Behrad | ▼ Sell | Open Market | 1,718 | $32K | 5/2/2024 |
| Russell Alan J | ▼ Sell | Open Market | 1,576 | $30K | 5/2/2024 |
| Donovan Joanne M. | ▼ Sell | Open Market | 3,682 | $70K | 5/2/2024 |
| KOCH KEVIN | ▼ Sell | Open Market | 3,152 | $60K | 5/2/2024 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2024 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2024 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2024 |
| Russell Alan J | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2024 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 10,417 | $0 | 5/1/2024 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 10,417 | $0 | 5/1/2024 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 8,029 | $15K | 2/9/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 8,029 | $161K | 2/9/2024 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 4,800 | $9K | 2/9/2024 |
| Derakhshan Behrad | ▼ Sell | Open Market | 4,800 | $96K | 2/9/2024 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 3,813 | $7K | 2/8/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 3,813 | $76K | 2/8/2024 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 4,600 | $9K | 2/8/2024 |
| Derakhshan Behrad | ▼ Sell | Open Market | 4,600 | $92K | 2/8/2024 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 17,993 | $35K | 2/7/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 17,993 | $360K | 2/7/2024 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 600 | $1K | 2/7/2024 |
| Derakhshan Behrad | ▼ Sell | Open Market | 600 | $12K | 2/7/2024 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 90,000 | $174K | 1/23/2024 |
| Carruthers R Michael | ▼ Sell | Open Market | 90,000 | $1.4M | 1/23/2024 |
| Peter A. Thompson | ▲ Buy | Open Market | 454,545 | $5.0M | 1/23/2024 |
| ORBIMED ADVISORS LLC | ▲ Buy | Open Market | 454,545 | $5.0M | 1/23/2024 |
| MOORE JOHN R | ▼ Sell | Open Market | 8,497 | $89K | 12/27/2023 |
| Fox Jonathan C | ▲ Buy | Open Market | 10,857 | $101K | 12/26/2023 |
| Russell Alan J | ▼ Sell | Open Market | 172,585 | $1.6M | 12/26/2023 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 10,000 | $7K | 6/22/2023 |
| Derakhshan Behrad | ▼ Sell | Open Market | 1,747 | $16K | 5/2/2023 |
| MOORE JOHN R | ▼ Sell | Open Market | 1,897 | $17K | 5/2/2023 |
| Carruthers R Michael | ▼ Sell | Open Market | 1,336 | $12K | 5/2/2023 |
| Russell Alan J | ▼ Sell | Open Market | 1,602 | $14K | 5/2/2023 |
| Donovan Joanne M. | ▼ Sell | Open Market | 3,254 | $29K | 5/2/2023 |
| KOCH KEVIN | ▼ Sell | Open Market | 3,203 | $29K | 5/2/2023 |
| Derakhshan Behrad | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2023 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2023 |
| Carruthers R Michael | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2023 |
| Russell Alan J | ▲ Buy | Option Exercise | 5,208 | $0 | 5/1/2023 |
| Donovan Joanne M. | ▲ Buy | Option Exercise | 10,416 | $0 | 5/1/2023 |
| KOCH KEVIN | ▲ Buy | Option Exercise | 10,416 | $0 | 5/1/2023 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 4,730 | $9K | 10/3/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 4,730 | $46K | 10/3/2022 |
| Peter A. Thompson | ▲ Buy | Open Market | 484,496 | $5.0M | 9/16/2022 |
| ORBIMED ADVISORS LLC | ▲ Buy | Open Market | 484,496 | $5.0M | 9/16/2022 |
| Novo Holdings A/S | ▲ Buy | Open Market | 484,496 | $5.0M | 9/14/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 4,730 | $9K | 9/6/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 2,379 | $26K | 9/6/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 2,351 | $26K | 9/6/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 4,730 | $9K | 8/3/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 4,502 | $3K | 8/3/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 9,232 | $86K | 8/3/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 1,046 | $2K | 7/6/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 1,046 | $9K | 7/6/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 3,684 | $7K | 7/5/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 4,502 | $3K | 7/5/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 8,186 | $68K | 7/5/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 13,508 | $10K | 6/21/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 17,570 | $34K | 6/21/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 31,078 | $227K | 6/21/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 22,127 | $43K | 6/17/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 22,127 | $146K | 6/17/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 14,722 | $28K | 6/16/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 14,722 | $91K | 6/16/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 18,075 | $13K | 6/15/2022 |
| MOORE JOHN R | ▲ Buy | Option Exercise | 585 | $1K | 6/15/2022 |
| MOORE JOHN R | ▼ Sell | Open Market | 585 | $4K | 6/15/2022 |
AI Market Commentary
AI-generatedAll commentary →Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.
October 10, 2026
Edgewise Therapeutics Doses First Patient in Phase 2 Trial
Edgewise Therapeutics has dosed the first participant in its Phase 2 EQUINOX-HFpEF trial for EDG-15400, a drug intended to treat heart failure with preserved ejection fraction. This marks a key clinical milestone for the company. The stock is currently trading near its 52-week high, with analysts maintaining an average price target of $52.62.
Edgewise Therapeutics Doses First Patient in Phase 2 Trial. Edgewise Therapeutics has dosed the first participant in its Phase 2 EQUINOX-HFpEF trial for EDG-15400, a drug intended to treat heart failure with preserved ejection fraction. This marks a key clinical milestone for the company. The stock is currently trading near its 52-week high, with analysts maintaining an average price target of $52.62.