GRCE
ACOG
SLGL
ETON
SNWV

Opaleye Management Inc.

Known title: 10% OwnerCIK: 0001595855

Opaleye Management Inc.'s purchase track record

How the stock did after each of Opaleye Management Inc.'s open-market purchases, measured from the purchase date. Several fills within a week count as one purchase.

Purchases measured
63
of 83 since August 17, 2021
Stock higher 6 months later
59%
3 months: 68%
Median 6-month return
+20.4%
3 months: +19.5%
Beat the S&P 500
54%
median +12.1% vs. index
PurchaseStockAmount3 months6 months
9/29/2026GRCE$140Kpendingpending
9/24/2026ACOG$436Kpendingpending
9/21/2026GRCE$32Kpendingpending
9/14/2026ACOG$1.06Mpendingpending
9/8/2026GRCE$32Kpendingpending
7/10/2026SLGL$142K-2.9%pending
7/1/2026SLGL$145K+3.2%pending
6/25/2026ACOG$976K+31.9%pending
6/15/2026ACOG$27K+45.4%pending
6/5/2026ACOG$261K+63.6%pending
5/27/2026ACOG$435K+64.2%pending
5/20/2026SLGL$101K+20.4%pending
5/15/2026ACOG$337K+46.8%pending
5/12/2026SLGL$232K+15.9%pending
3/24/2026ACOG$169K+17.6%+59.1%
3/24/2026SLGL$2.86M-10.9%-24.1%
3/12/2026ACOG$110K+3.3%+52.1%
3/2/2026ACOG$823K+9.3%+59.3%
2/20/2026ACOG$1.03M0.0%+67.2%
2/13/2026SLGL$18K+8.2%+26.0%
2/2/2026SLGL$6K+20.5%+31.0%
1/22/2026SLGL$193K+25.7%+40.1%
12/30/2025SLGL$2.53M+86.6%+74.6%
12/22/2025SLGL$482K+57.0%+75.0%
12/12/2025SLGL$114K+115.3%+88.3%

Computed by MarketWall from SEC Form 4 filings and daily closing prices (close on the purchase date to the close about 3 and 6 months later). Companies that have since delisted are not included. Past results, not investment advice.

Associated companies

this person other insiders at GRCE

AI Market Commentary

AI-generatedAll commentary →

Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.

October 1, 2026

Alpha Cognition Releases 180-Day Data on CONVERGE Program. Alpha Cognition has published results from a 180‑day study of its CONVERGE program. The data covers patients who are taking ZUNVEYL, donepezil, galantamine or rivastigmine. The release gives a clearer view of how the program performs in real‑world use. Investors can use the information to assess the company’s therapeutic strategy.

this person other insiders at ACOG

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September 30, 2026

Sol-Gel Technologies Announces Investor Day for SGT-610. Sol-Gel Technologies has announced it will host a KOL Investor Day for its SGT-610 product on October 14, 2026. The event will bring together key opinion leaders to discuss the product's progress and future plans. Investors can expect additional details on SGT-610’s development and potential market impact.

this person other insiders at SLGL

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October 14, 2026

Eton Secures U.S. License for LIBERVANT Buccal Film. Eton Pharmaceuticals has signed an exclusive U.S. license and supply agreement with Aquestive Therapeutics for LIBERVANT, a buccal film designed to treat seizure clusters in epilepsy patients. The partnership will bring the product to market in April 2027, expanding Eton’s epilepsy portfolio. The deal positions Eton to capture a niche therapeutic area and could support future revenue growth.

this person other insiders at ETON
this person other insiders at SNWV

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October 14, 2026

Harrow (HROW) gains analyst support and conference buzz amid turnaround focus. Recent coverage highlights growing attention on Harrow’s ophthalmic pipeline, with analysts maintaining a $63 price target and an average target of $65. A recent conference has generated buzz, while options activity suggests market participants are watching the stock closely. The company’s Q3 results are expected to confirm whether the turnaround plan is taking hold.

this person other insiders at HROW

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September 28, 2026

Codexis Signs siRNA Manufacturing Deal. Codexis has entered an agreement with an unnamed siRNA drug innovator to use its ECO Synthesis platform for stereo-defined fragment synthesis. This partnership highlights the company's manufacturing capabilities in a growing therapeutic area. The stock is currently trading near its 52-week low, with recent price action showing rejection at support levels.

this person other insiders at CDXS

Transaction History

GRCE▲ Buy$3K
GRCE▲ Buy$41K
ACOG▲ Buy$166K
GRCE▲ Buy$79K
GRCE▲ Buy$16K
ACOG▲ Buy$114K
ACOG▲ Buy$157K
GRCE▲ Buy$11K
GRCE▲ Buy$21K
ACOG▲ Buy$455K
ACOG▲ Buy$228K
ACOG▲ Buy$29K
ACOG▲ Buy$351K
SLGL▲ Buy$98K
SLGL▲ Buy$109K
SLGL▲ Buy$213K
GRCE▲ Buy$12K
SLGL▲ Buy$233K
SLGL▲ Buy$33K
GRCE▲ Buy$20K
SLGL▲ Buy$64K
SLGL▲ Buy$145K
SLGL▲ Buy$62K
SLGL▲ Buy$54K
SLGL▲ Buy$341K
SLGL▲ Buy$15K
SLGL▲ Buy$714K
SLGL▲ Buy$1.4M
SLGL▲ Buy$344K
GRCE▲ Buy$24K
SLGL▲ Buy$68K
ACOG▲ Buy$400K
ACOG▲ Buy$23K
ACOG▲ Buy$1K
ACOG▲ Buy$389K
ACOG▲ Buy$1.1M
ACOG▲ Buy$78K
SLGL▲ Buy$68K
ETON▼ Sell$563K
ETON▼ Sell$500K
SLGL▲ Buy$57K
SLGL▲ Buy$17K
SLGL▲ Buy$22K
ETON▼ Sell$257K
ETON▼ Sell$767K
ETON▼ Sell$380K
SLGL▲ Buy$101K
ETON▼ Sell$935K
ETON▼ Sell$2.4M
SLGL▲ Buy$22K
ACOG▲ Buy$975K
ACOG▲ Buy$1K
ACOG▲ Buy$27K
ACOG▲ Buy$2K
ACOG▲ Buy$17K
ACOG▲ Buy$35K
ACOG▲ Buy$149K
ACOG▲ Buy$59K
ACOG▲ Buy$416K
ACOG▲ Buy$12K
ACOG▲ Buy$7K
ACOG▲ Buy$91K
ACOG▲ Buy$50K
SLGL▲ Buy$101K
ACOG▲ Buy$99K
ACOG▲ Buy$97K
SLGL▲ Buy$130K
SLGL▲ Buy$102K
SNWV▼ Sell$8K
SNWV▼ Sell$162K
SNWV▼ Sell$388K
SNWV▼ Sell$16K
SNWV▼ Sell$403K
SNWV▼ Sell$17K
SNWV▼ Sell$809K
SNWV▼ Sell$46K
SNWV▼ Sell$4K
SNWV▼ Sell$231K
SNWV▼ Sell$102K
ACOG▲ Buy$9K
ACOG▲ Buy$51K
ACOG▲ Buy$39K
ACOG▲ Buy$47K
ACOG▲ Buy$23K
SLGL▲ Buy$2.5M
SLGL▲ Buy$360K
ACOG▲ Buy$12K
ACOG▲ Buy$14K
ACOG▲ Buy$8K
ACOG▲ Buy$42K
ACOG▲ Buy$33K
ACOG▲ Buy$13K
ACOG▲ Buy$11K
ACOG▲ Buy$244K
ACOG▲ Buy$29K
ACOG▲ Buy$115K
HROW▼ Sell$5.3M
HROW▼ Sell$169K
ACOG▲ Buy$267K
ACOG▲ Buy$29K
HROW▼ Sell$51K
HROW▼ Sell$2.3M
ACOG▲ Buy$116K
ACOG▲ Buy$22K
HROW▼ Sell$271K
ACOG▲ Buy$4K
ACOG▲ Buy$311K
ACOG▲ Buy$29K
ACOG▲ Buy$565K
ACOG▲ Buy$25K
ACOG▲ Buy$16K
ACOG▲ Buy$58K
SLGL▲ Buy$18K
SLGL▲ Buy$6K
SLGL▲ Buy$6K
SLGL▲ Buy$64K
SLGL▲ Buy$123K
HROW▼ Sell$1.1M
SLGL▲ Buy$9K
SLGL▲ Buy$100K
SLGL▲ Buy$945K
SLGL▲ Buy$1.5M
SLGL▲ Buy$362K
SLGL▲ Buy$68K
SLGL▲ Buy$11K
SLGL▲ Buy$42K
SLGL▲ Buy$110K
SLGL▲ Buy$3K
SLGL▲ Buy$12K
SLGL▲ Buy$18K
SLGL▲ Buy$95K
SLGL▲ Buy$162K
CDXS▼ Sell$409K
CDXS▼ Sell$14K
CDXS▼ Sell$184K
CDXS▼ Sell$4K
SLGL▲ Buy$38K
CDXS▼ Sell$258K
CDXS▼ Sell$9K
SLGL▲ Buy$213
SLGL▲ Buy$207K
CDXS▼ Sell$1.7M
CDXS▼ Sell$53K
CDXS▼ Sell$324K
CDXS▼ Sell$963K
CDXS▼ Sell$24K
CDXS▼ Sell$356K
CDXS▼ Sell$6K
CDXS▼ Sell$17K
CDXS▼ Sell$503K
SNWV▲ Buy$38K
CDXS▲ Buy$2K
CDXS▲ Buy$226K
CDXS▲ Buy$4K
CDXS▲ Buy$24K
CDXS▲ Buy$282K
CDXS▲ Buy$239K
CDXS▲ Buy$114K
CDXS▲ Buy$221K
CDXS▲ Buy$225K
HROW▼ Sell$462K
ETON▲ Buy$46K
ETON▲ Buy$79K
HROW▼ Sell$462K
HROW▼ Sell$54K
HROW▼ Sell$90K
CDXS▲ Buy$12K
CDXS▲ Buy$5.5M
HROW▼ Sell$133K
HROW▼ Sell$259K
CDXS▲ Buy$46K
CDXS▲ Buy$58K
SNWV▲ Buy$127K
SNWV▲ Buy$76K
CDXS▲ Buy$56K
CDXS▲ Buy$94K
CDXS▲ Buy$149K
CDXS▲ Buy$56K
CDXS▲ Buy$198K
CDXS▲ Buy$173K
CDXS▲ Buy$12K
CDXS▲ Buy$87K
CDXS▲ Buy$236K
CDXS▲ Buy$18
HROW▼ Sell$148K
HROW▼ Sell$150K
CDXS▲ Buy$216K
CDXS▲ Buy$261K
CDXS▲ Buy$27K
CDXS▲ Buy$145K
CDXS▲ Buy$133K
HROW▼ Sell$140K
CDXS▲ Buy$441K
CDXS▲ Buy$60K
CDXS▲ Buy$51K
CDXS▲ Buy$94K
CDXS▲ Buy$193K
CDXS▲ Buy$90K
HROW▼ Sell$712K
CDXS▲ Buy$47K

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