SYRE · Spyre Therapeutics Inc. Common Stock
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| Quinn Anthony G. President & CEO | ▲ Buy | Open Market | 550,540 Shares held | 3/16/2022 | View profile |
| Cameron Turtle Chief Executive Officer | ▼ Sell | Open Market | 537,540 Shares held | 10/1/2026 | View profile |
| Alspaugh Jonathan Chief Financial Officer | ▲ Buy | Open Market | 165,372 Shares held | 3/11/2022 | View profile |
| Shanafelt Armen Director | ▲ Buy | Open Market | 150,000 Shares held | 12/13/2021 | View profile |
| Marcio Souza President and CEO | ▲ Buy | Open Market | 90,000 Shares held | 8/25/2022 | View profile |
| Scott L. Burrows Chief Financial Officer | ▼ Sell | Open Market | 79,762 Shares held | 10/1/2026 | View profile |
| Michael Thomas Henderson Director | ▼ Sell | Open Market | 68,606 Shares held | 6/22/2026 | View profile |
| Hanley Jr. Michael Conick Chief Commercial Officer | ▲ Buy | Open Market | 36,200 Shares held | 6/8/2022 | View profile |
| Jeffrey W. Albers Director | ▼ Sell | Open Market | 9,360 Shares held | 8/7/2026 | View profile |
| King-Jones Heidy See Remarks | ▼ Sell | Open Market | 2,845 Shares held | 10/1/2026 | View profile |
| Fairmount Funds Management LLC Director | ▼ Sell | Open Market | 0 Shares held | 6/23/2026 | View profile |
| Sheldon Sloan Chief Medical Officer | ▼ Sell | Open Market | 0 Shares held | 7/1/2026 | View profile |
Transaction History
| King-Jones Heidy | ▲ Buy | Option Exercise | 28,933 | $420K | 10/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 400 | $36K | 10/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 16,605 | $1.5M | 10/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 7,228 | $660K | 10/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 2,100 | $195K | 10/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 2,600 | $243K | 10/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 600 | $53K | 10/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 2,683 | $242K | 10/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 2,638 | $241K | 10/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 3,989 | $368K | 10/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 4,990 | $466K | 10/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 100 | $9K | 10/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 7,500 | $109K | 10/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 600 | $53K | 10/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 1,500 | $135K | 10/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 2,100 | $193K | 10/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 3,071 | $285K | 10/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 229 | $21K | 10/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 17,500 | $254K | 9/30/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 17,500 | $1.6M | 9/30/2026 |
| King-Jones Heidy | ▲ Buy | Option Exercise | 400 | $6K | 9/2/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 400 | $36K | 9/2/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 18,232 | $1.6M | 9/2/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 400 | $36K | 9/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 7,500 | $109K | 9/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 900 | $78K | 9/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 2,016 | $177K | 9/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 8,400 | $732K | 9/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 3,700 | $326K | 9/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 400 | $36K | 9/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 2,500 | $216K | 9/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 16,548 | $1.4M | 9/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 4,845 | $419K | 9/1/2026 |
| King-Jones Heidy | ▲ Buy | Option Exercise | 27,999 | $406K | 9/1/2026 |
| King-Jones Heidy | ▼ Sell | Open Market | 6,206 | $547K | 9/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 4,384 | $382K | 9/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 200 | $18K | 9/1/2026 |
| Jeffrey W. Albers | ▼ Sell | Open Market | 10,000 | $1.0M | 8/7/2026 |
| Jeffrey W. Albers | ▲ Buy | Option Exercise | 5,000 | $52K | 8/7/2026 |
| Jeffrey W. Albers | ▼ Sell | Open Market | 5,000 | $522K | 8/7/2026 |
| Jeffrey W. Albers | ▼ Sell | Open Market | 8,000 | $835K | 8/7/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 7,500 | $109K | 8/3/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 5,100 | $486K | 8/3/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 2,300 | $221K | 8/3/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 100 | $10K | 8/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 800 | $75K | 8/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 7,157 | $681K | 8/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 5,635 | $541K | 8/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 1,392 | $135K | 8/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 16 | $2K | 8/3/2026 |
| Sheldon Sloan | ▲ Buy | Option Exercise | 8,334 | $229K | 7/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 6,500 | $569K | 7/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 1,834 | $162K | 7/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 10,176 | $890K | 7/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 4,234 | $373K | 7/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 590 | $52K | 7/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 7,500 | $109K | 7/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 5,775 | $506K | 7/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 1,725 | $152K | 7/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 15,000 | $218K | 6/25/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 5,000 | $436K | 6/25/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 10,000 | $871K | 6/25/2026 |
| Fairmount Funds Management LLC | ▼ Sell | Other | 666,680 | — | 6/23/2026 |
| Fairmount Funds Management LLC | ▼ Sell | Open Market | 4,684,781 | $399.7M | 6/23/2026 |
| Michael Thomas Henderson | ▼ Sell | Open Market | 20,000 | $2.0M | 6/22/2026 |
| Sheldon Sloan | ▲ Buy | Option Exercise | 8,333 | $229K | 6/3/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 8,333 | $625K | 6/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 3,557 | $247K | 6/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 8,149 | $575K | 6/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 3,294 | $235K | 6/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 7,500 | $109K | 6/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 1,801 | $126K | 6/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 2,599 | $184K | 6/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 3,100 | $223K | 6/1/2026 |
| Michael Thomas Henderson | ▼ Sell | Open Market | 2,404 | $174K | 5/8/2026 |
| Michael Thomas Henderson | ▼ Sell | Open Market | 33,513 | $2.5M | 5/8/2026 |
| Michael Thomas Henderson | ▼ Sell | Open Market | 19,269 | $1.5M | 5/8/2026 |
| Michael Thomas Henderson | ▼ Sell | Open Market | 24,814 | $1.9M | 5/8/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 10,358 | $764K | 5/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 12,777 | $932K | 5/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 12,500 | $181K | 5/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 12,500 | $892K | 5/1/2026 |
| Sheldon Sloan | ▲ Buy | Option Exercise | 78,333 | $2.2M | 5/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 21,306 | $1.5M | 5/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 19,656 | $1.4M | 5/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 8,777 | $628K | 5/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 5,059 | $377K | 5/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 400 | $30K | 5/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 5,300 | $369K | 5/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 3,600 | $255K | 5/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 1,000 | $72K | 5/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 3,100 | $227K | 5/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 1,700 | $126K | 5/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 300 | $22K | 5/1/2026 |
| Sheldon Sloan | ▲ Buy | Option Exercise | 7,958 | $172K | 4/1/2026 |
| Sheldon Sloan | ▼ Sell | Open Market | 7,958 | $398K | 4/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 2,656 | $133K | 4/1/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 12,344 | $607K | 4/1/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 7,500 | $109K | 4/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 6,200 | $305K | 4/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 1,300 | $65K | 4/1/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 200 | $8K | 3/3/2026 |
| Scott L. Burrows | ▲ Buy | Option Exercise | 2,500 | $36K | 3/3/2026 |
| Scott L. Burrows | ▼ Sell | Open Market | 2,300 | $93K | 3/3/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 5,900 | $246K | 3/2/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 9,100 | $387K | 3/2/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 957 | $30K | 2/2/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 14,043 | $462K | 2/2/2026 |
| Michael Thomas Henderson | ▼ Sell | Other | 63,227 | $0 | 1/21/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 12,709 | $387K | 1/2/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 2,191 | $70K | 1/2/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 100 | $3K | 1/2/2026 |
| Cameron Turtle | ▼ Sell | Open Market | 10,995 | $316K | 12/1/2025 |
| Cameron Turtle | ▼ Sell | Open Market | 4,005 | $119K | 12/1/2025 |
| Cameron Turtle | ▼ Sell | Open Market | 28,155 | $651K | 11/3/2025 |
| Cameron Turtle | ▼ Sell | Open Market | 16,845 | $399K | 11/3/2025 |
| Scott L. Burrows | ▼ Sell | Open Market | 18,428 | $300K | 9/2/2025 |
| Michael Thomas Henderson | ▼ Sell | Other | 105,379 | $0 | 1/10/2025 |
| Jeffrey W. Albers | ▼ Sell | Open Market | 6,700 | $246K | 11/6/2024 |
| Jeffrey W. Albers | ▼ Sell | Open Market | 300 | $11K | 10/25/2024 |
| Scott L. Burrows | ▼ Sell | Open Market | 18,531 | $522K | 9/3/2024 |
| Fairmount Funds Management LLC | ▲ Buy | Option Exercise | 3,639,680 | $0 | 4/25/2024 |
| Cameron Turtle | ▲ Buy | Grant | 400 | $4K | 2/15/2024 |
| Fairmount Funds Management LLC | ▼ Sell | Other | 3,435,480 | $0 | 12/29/2023 |
| Fairmount Funds Management LLC | ▼ Sell | Other | 406,038 | $0 | 12/29/2023 |
| Fairmount Funds Management LLC | ▼ Sell | Other | 406,038 | $0 | 12/29/2023 |
| Scott L. Burrows | ▲ Buy | Grant | 134,953 | $0 | 12/22/2023 |
| Fairmount Funds Management LLC | ▼ Sell | Other | 3,435,480 | $0 | 11/24/2023 |
| Cameron Turtle | ▼ Sell | Other | 723,440 | $0 | 11/24/2023 |
| Marcio Souza | ▲ Buy | Open Market | 90,000 | $50K | 8/25/2022 |
| Hanley Jr. Michael Conick | ▲ Buy | Open Market | 28,200 | $20K | 6/8/2022 |
| Quinn Anthony G. | ▲ Buy | Open Market | 80,079 | $188K | 3/16/2022 |
| Quinn Anthony G. | ▲ Buy | Open Market | 42,417 | $79K | 3/15/2022 |
| Quinn Anthony G. | ▲ Buy | Open Market | 67,472 | $130K | 3/14/2022 |
| Alspaugh Jonathan | ▲ Buy | Open Market | 75,000 | $156K | 3/11/2022 |
| Quinn Anthony G. | ▲ Buy | Open Market | 34,777 | $72K | 3/11/2022 |
| Shanafelt Armen | ▲ Buy | Open Market | 14,685 | $54K | 12/13/2021 |
| Shanafelt Armen | ▲ Buy | Open Market | 13,516 | $49K | 12/10/2021 |
| Quinn Anthony G. | ▲ Buy | Open Market | 10,526 | $39K | 12/10/2021 |
| Quinn Anthony G. | ▲ Buy | Open Market | 43,108 | $159K | 12/9/2021 |
| Shanafelt Armen | ▲ Buy | Open Market | 121,799 | $447K | 12/9/2021 |
| Alspaugh Jonathan | ▲ Buy | Open Market | 50,000 | $186K | 12/9/2021 |
| Alspaugh Jonathan | ▲ Buy | Open Market | 7,200 | $48K | 8/18/2021 |
| Alspaugh Jonathan | ▲ Buy | Open Market | 23,392 | $152K | 8/17/2021 |
| Alspaugh Jonathan | ▲ Buy | Open Market | 9,780 | $62K | 8/16/2021 |
AI Market Commentary
AI-generatedAll commentary →Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.
October 6, 2026
Spyre Therapeutics Launches $350M Public Offering, Stock Drops
Spyre Therapeutics has priced a $350 million public offering of common stock, which led to a decline in the share price on the launch day. The company also announced inducement awards to support its growth. Analysts from JP Morgan and BTIG have begun coverage, citing a target price around $110 to $121. The offering and analyst interest may influence the stock’s short‑term trajectory.
Spyre Therapeutics Launches $350M Public Offering, Stock Drops. Spyre Therapeutics has priced a $350 million public offering of common stock, which led to a decline in the share price on the launch day. The company also announced inducement awards to support its growth. Analysts from JP Morgan and BTIG have begun coverage, citing a target price around $110 to $121. The offering and analyst interest may influence the stock’s short‑term trajectory.