SPRO · Spero Therapeutics Inc. Common Stock
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| Aquilo Capital Management, LLC 10% Owner | ▼ Sell | Open Market | 3,419,435 Shares held | 9/22/2022 | View profile |
| Shukla Sath Chief Financial Officer | ▼ Sell | Open Market | 1,736,883 Shares held | 2/5/2025 | View profile |
| Rajavelu Esther See Remarks | ▼ Sell | Open Market | 986,851 Shares held | 5/4/2026 | View profile |
| HAMED KAMAL Chief Medical Officer | ▼ Sell | Open Market | 788,117 Shares held | 2/2/2024 | View profile |
| Keutzer Timothy Chief Development Officer | ▼ Sell | Open Market | 742,506 Shares held | 2/6/2026 | View profile |
| Mahadevia Ankit CEO and President | ▼ Sell | Open Market | 703,294 Shares held | 8/28/2025 | View profile |
| JOSEPH TAMARA L Chief Legal Officer | ▼ Sell | Open Market | 531,615 Shares held | 2/2/2024 | View profile |
| Zack Debra Chief Medical Officer | ▲ Buy | Grant | 162,311 Shares held | 8/3/2026 | View profile |
| Deshpande Milind Director | ▲ Buy | Grant | 101,454 Shares held | 6/23/2026 | View profile |
| Smith Cynthia Director | ▲ Buy | Grant | 85,000 Shares held | 6/23/2026 | View profile |
| THOMAS FRANK E Director | ▲ Buy | Grant | 85,000 Shares held | 6/23/2026 | View profile |
| Jackson Scott Thomas Director | ▲ Buy | Grant | 85,000 Shares held | 6/23/2026 | View profile |
| Tregoning Kathleen Director | ▲ Buy | Grant | 85,000 Shares held | 6/23/2026 | View profile |
| VINK PATRICK V.J.J. Director | ▲ Buy | Grant | 85,000 Shares held | 6/23/2026 | View profile |
| Pottage John C Jr Director | ▲ Buy | Grant | 85,000 Shares held | 6/23/2026 | View profile |
| Larkin Cristina Chief Operating Officer | ▲ Buy | Grant | 63,581 Shares held | 2/1/2022 | View profile |
| Melnick David A. Chief Medical Officer | ▲ Buy | Grant | 62,081 Shares held | 2/1/2022 | View profile |
Transaction History
| Zack Debra | ▲ Buy | Grant | 162,311 | $0 | 8/3/2026 |
| Deshpande Milind | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| Tregoning Kathleen | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| Smith Cynthia | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| VINK PATRICK V.J.J. | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| THOMAS FRANK E | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| Jackson Scott Thomas | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| Pottage John C Jr | ▲ Buy | Grant | 10,000 | $0 | 6/23/2026 |
| Rajavelu Esther | ▼ Sell | Open Market | 25,240 | $63K | 5/4/2026 |
| Rajavelu Esther | ▼ Sell | Open Market | 37,101 | $88K | 2/6/2026 |
| Rajavelu Esther | ▼ Sell | Open Market | 50,816 | $120K | 2/6/2026 |
| Keutzer Timothy | ▼ Sell | Open Market | 18,652 | $44K | 2/6/2026 |
| Keutzer Timothy | ▼ Sell | Open Market | 3,471 | $8K | 2/4/2026 |
| Keutzer Timothy | ▼ Sell | Open Market | 24,224 | $52K | 2/3/2026 |
| Keutzer Timothy | ▼ Sell | Open Market | 18,891 | $42K | 2/2/2026 |
| Rajavelu Esther | ▼ Sell | Open Market | 18,442 | $41K | 2/2/2026 |
| Rajavelu Esther | ▲ Buy | Grant | 249,000 | $0 | 2/2/2026 |
| Keutzer Timothy | ▲ Buy | Grant | 68,000 | $0 | 2/2/2026 |
| Rajavelu Esther | ▼ Sell | Open Market | 40,270 | $95K | 11/7/2025 |
| Mahadevia Ankit | ▼ Sell | Open Market | 6,572 | $13K | 8/28/2025 |
| Keutzer Timothy | ▼ Sell | Open Market | 1,695 | $3K | 8/28/2025 |
| VINK PATRICK V.J.J. | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Pottage John C Jr | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Smith Cynthia | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| THOMAS FRANK E | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Mahadevia Ankit | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Deshpande Milind | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Jackson Scott Thomas | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Tregoning Kathleen | ▲ Buy | Grant | 20,000 | $0 | 6/12/2025 |
| Rajavelu Esther | ▲ Buy | Grant | 185,000 | $0 | 5/2/2025 |
| Keutzer Timothy | ▼ Sell | Open Market | 3,974 | $3K | 2/5/2025 |
| Keutzer Timothy | ▼ Sell | Open Market | 27,643 | $22K | 2/5/2025 |
| Keutzer Timothy | ▼ Sell | Open Market | 24,920 | $19K | 2/5/2025 |
| Rajavelu Esther | ▼ Sell | Open Market | 20,689 | $16K | 2/5/2025 |
| Shukla Sath | ▼ Sell | Open Market | 6,139 | $5K | 2/5/2025 |
| Shukla Sath | ▼ Sell | Open Market | 42,786 | $33K | 2/5/2025 |
| Shukla Sath | ▼ Sell | Open Market | 106,408 | $83K | 2/5/2025 |
| Mahadevia Ankit | ▼ Sell | Open Market | 13,959 | $11K | 2/5/2025 |
| Mahadevia Ankit | ▼ Sell | Open Market | 55,260 | $43K | 2/5/2025 |
| Keutzer Timothy | ▲ Buy | Grant | 266,139 | $0 | 2/3/2025 |
| Rajavelu Esther | ▲ Buy | Grant | 100,000 | $0 | 2/3/2025 |
| Rajavelu Esther | ▲ Buy | Grant | 266,139 | $0 | 2/3/2025 |
| Shukla Sath | ▲ Buy | Grant | 751,407 | $0 | 2/3/2025 |
| Rajavelu Esther | ▼ Sell | Open Market | 17,245 | $22K | 11/8/2024 |
| Rajavelu Esther | ▼ Sell | Open Market | 23,351 | $31K | 11/7/2024 |
| Mahadevia Ankit | ▼ Sell | Open Market | 5,912 | $8K | 8/27/2024 |
| Keutzer Timothy | ▼ Sell | Open Market | 2,213 | $3K | 8/27/2024 |
| Shukla Sath | ▼ Sell | Open Market | 2,757 | $4K | 8/27/2024 |
| Shukla Sath | ▼ Sell | Open Market | 17,641 | $23K | 8/5/2024 |
| Shukla Sath | ▼ Sell | Open Market | 14,800 | $20K | 8/2/2024 |
| Jackson Scott Thomas | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| Deshpande Milind | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| Mahadevia Ankit | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| VINK PATRICK V.J.J. | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| Tregoning Kathleen | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| Smith Cynthia | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| THOMAS FRANK E | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| Pottage John C Jr | ▲ Buy | Grant | 20,000 | $0 | 5/29/2024 |
| Shukla Sath | ▼ Sell | Open Market | 45,093 | $65K | 2/5/2024 |
| Keutzer Timothy | ▼ Sell | Open Market | 30,971 | $42K | 2/2/2024 |
| Mahadevia Ankit | ▼ Sell | Open Market | 63,795 | $87K | 2/2/2024 |
| JOSEPH TAMARA L | ▼ Sell | Open Market | 30,906 | $42K | 2/2/2024 |
| HAMED KAMAL | ▼ Sell | Open Market | 28,075 | $38K | 2/2/2024 |
| Shukla Sath | ▼ Sell | Open Market | 30,901 | $42K | 2/2/2024 |
| Keutzer Timothy | ▲ Buy | Grant | 239,731 | $0 | 2/1/2024 |
| JOSEPH TAMARA L | ▲ Buy | Grant | 239,731 | $0 | 2/1/2024 |
| HAMED KAMAL | ▲ Buy | Grant | 239,731 | $0 | 2/1/2024 |
| Rajavelu Esther | ▲ Buy | Grant | 119,866 | $0 | 2/1/2024 |
| Shukla Sath | ▲ Buy | Grant | 679,501 | $0 | 2/1/2024 |
| Rajavelu Esther | ▲ Buy | Grant | 300,000 | $0 | 11/13/2023 |
| Mahadevia Ankit | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| Pottage John C Jr | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| Smith Cynthia | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| THOMAS FRANK E | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| Deshpande Milind | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| Tregoning Kathleen | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| VINK PATRICK V.J.J. | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| Jackson Scott Thomas | ▲ Buy | Grant | 20,000 | $0 | 10/5/2023 |
| HAMED KAMAL | ▼ Sell | Open Market | 39,496 | $50K | 9/13/2023 |
| Shukla Sath | ▼ Sell | Open Market | 4,163 | $5K | 8/29/2023 |
| Keutzer Timothy | ▼ Sell | Open Market | 1,854 | $2K | 8/28/2023 |
| JOSEPH TAMARA L | ▼ Sell | Open Market | 1,854 | $2K | 8/28/2023 |
| Mahadevia Ankit | ▼ Sell | Open Market | 9,040 | $11K | 8/28/2023 |
| Shukla Sath | ▼ Sell | Open Market | 1,854 | $2K | 8/28/2023 |
| Shukla Sath | ▲ Buy | Grant | 266,000 | $0 | 8/1/2023 |
| HAMED KAMAL | ▲ Buy | Grant | 140,000 | $0 | 6/12/2023 |
| Mahadevia Ankit | ▼ Sell | Open Market | 12,286 | $22K | 2/3/2023 |
| Keutzer Timothy | ▼ Sell | Open Market | 3,394 | $6K | 2/2/2023 |
| JOSEPH TAMARA L | ▼ Sell | Open Market | 3,394 | $6K | 2/2/2023 |
| Shukla Sath | ▼ Sell | Open Market | 9,504 | $17K | 2/2/2023 |
| Keutzer Timothy | ▲ Buy | Grant | 265,957 | $0 | 2/1/2023 |
| JOSEPH TAMARA L | ▲ Buy | Grant | 265,957 | $0 | 2/1/2023 |
| Shukla Sath | ▲ Buy | Grant | 265,957 | $0 | 2/1/2023 |
| HAMED KAMAL | ▲ Buy | Grant | 265,957 | $0 | 2/1/2023 |
| Mahadevia Ankit | ▲ Buy | Grant | 531,914 | $0 | 2/1/2023 |
| Aquilo Capital Management, LLC | ▼ Sell | Open Market | 1,335,512 | $3.0M | 9/22/2022 |
| Aquilo Capital Management, LLC | ▼ Sell | Open Market | 566,284 | $1.3M | 9/22/2022 |
| Jackson Scott Thomas | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| Deshpande Milind | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| Pottage John C Jr | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| Smith Cynthia | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| THOMAS FRANK E | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| Tregoning Kathleen | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| VINK PATRICK V.J.J. | ▲ Buy | Grant | 15,000 | $0 | 9/15/2022 |
| HAMED KAMAL | ▲ Buy | Grant | 210,000 | $0 | 9/12/2022 |
| Shukla Sath | ▼ Sell | Open Market | 6,017 | $5K | 8/29/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 39,727 | $208K | 4/26/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 16,885 | $148K | 3/30/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 33,115 | $291K | 3/30/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 15,702 | $120K | 3/14/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 8,006 | $61K | 3/14/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 29,729 | $283K | 2/28/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 15,104 | $144K | 2/28/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 14,828 | $137K | 2/18/2022 |
| JOSEPH TAMARA L | ▲ Buy | Grant | 38,014 | $0 | 2/1/2022 |
| Keutzer Timothy | ▲ Buy | Grant | 38,014 | $0 | 2/1/2022 |
| Mahadevia Ankit | ▲ Buy | Grant | 134,168 | $0 | 2/1/2022 |
| Larkin Cristina | ▲ Buy | Grant | 38,014 | $0 | 2/1/2022 |
| Shukla Sath | ▲ Buy | Grant | 38,014 | $0 | 2/1/2022 |
| Melnick David A. | ▲ Buy | Grant | 38,014 | $0 | 2/1/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 125,000 | $1.4M | 1/31/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 1,599 | $17K | 1/24/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 48,488 | $602K | 1/18/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 8,867 | $115K | 1/10/2022 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 125,000 | $2.0M | 12/31/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 50,000 | $789K | 12/30/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 75,493 | $1.1M | 12/29/2021 |
| Mahadevia Ankit | ▲ Buy | Option Exercise | 8,000 | $47K | 12/27/2021 |
| Mahadevia Ankit | ▼ Sell | Open Market | 8,000 | $117K | 12/27/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 150,000 | $2.6M | 10/29/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 134,543 | $2.5M | 9/30/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 2,156 | $40K | 9/14/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 44,210 | $821K | 9/13/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 24,749 | $458K | 9/9/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 48,645 | $921K | 8/31/2021 |
| Aquilo Capital Management, LLC | ▲ Buy | Open Market | 44,042 | $787K | 8/30/2021 |
| Melnick David A. | ▲ Buy | Grant | 24,067 | $0 | 8/26/2021 |
| Mahadevia Ankit | ▲ Buy | Grant | 78,219 | $0 | 8/26/2021 |
| Larkin Cristina | ▲ Buy | Grant | 24,067 | $0 | 8/26/2021 |
| JOSEPH TAMARA L | ▲ Buy | Grant | 24,067 | $0 | 8/26/2021 |
| Keutzer Timothy | ▲ Buy | Grant | 24,067 | $0 | 8/26/2021 |
| Shukla Sath | ▲ Buy | Grant | 24,067 | $0 | 8/26/2021 |
AI Market Commentary
AI-generatedAll commentary →Synthesized from recent news and fundamentals/technical data -- not human analyst commentary or trader sentiment.
September 29, 2026
SPRO among stocks that gapped in Tuesday's session
Spero Therapeutics was listed as a gapping stock on Tuesday, meaning its price opened significantly different from the previous close. Such gaps often reflect a quick shift in market sentiment. The move occurs while the stock is near its $1.19 support level and has a neutral RSI around 49.
SPRO among stocks that gapped in Tuesday's session. Spero Therapeutics was listed as a gapping stock on Tuesday, meaning its price opened significantly different from the previous close. Such gaps often reflect a quick shift in market sentiment. The move occurs while the stock is near its $1.19 support level and has a neutral RSI around 49.